The COR2E Cryo-EM Facility in the Cell and Genome Sciences Building (UConn Health campus) supports single-particle cryo-EM from experimental design and specimen preparation through cryo-screening, data collection, and help with image analysis. The facility works with researchers at UConn Health, UConn Storrs, and outside academic and industry groups to make high-resolution structural biology more practical and affordable.
The facility combines automated, programmable grid preparation (VitriFlex) with a dedicated 100 kV cryo-transmission electron microscope (Thermo Scientific Tundra Cryo-TEM) for fast sample screening and single-particle structure determination. Grid surfaces are prepared with a PELCO easiGlow glow-discharge system. These tools handle both routine single-particle work and time-resolved or mixing experiments.
Services are offered full-service (facility-operated) or, after training, on a user-operated basis. New projects and reservations can be started with the New Project Request Form below or through Honeycrisp. For a project consultation, contact the Facility Director.
Announcements
Stay tuned!
UConn Health Campus Address
Cell and Genome Sciences Building
Lab:Room R2819, Office: R2830
Shipping Address
Cryo EM Facility (c/o Dr. Venkata Dandey)
Cell and Genome Sciences Building
400 Farmington Ave
Farmington, CT 06030
New Project Requests
All new cryo EM projects can be initiated by filling out the Project Request Form below. After your form is received, you will be contacted by the Director to arrange a meeting to discuss your pending project.